Our brains are the most complex machines known to humankind, but they have an Achilles heel: the very molecules that allow us to exist can also sabotage our minds. Here are gripping accounts of unruly molecules and the diseases that form in their wake.

A college student cannot remember if she has eaten breakfast. By dinner, she is strapped to a hospital bed, convinced she is battling zombies. A man planning to propose marriage instead becomes violently enraged, gripped by body spasms so severe that he nearly bites off his own tongue. One after another, poor farmers in South Carolina drop dead from a mysterious epidemic of dementia.

With an intoxicating blend of history and intrigue, Sara Manning Peskin invites readers to play medical detective, tracing each diagnosis from the patient to an ailing nervous system. Along the way, Peskin entertains with tales of the sometimes outlandish, often criticized, and forever devoted scientists who discovered it all.

Peskin never loses sight of the human impact of these conditions. Alzheimer's Disease is more than the gradual loss of a loved one; it can be a family's multigenerational curse. The proteins that abound in every cell of our bodies are not simply strings of oxygen, hydrogen, nitrogen, and carbon; they are the building blocks of our personalities and relationships. A Molecule Away from Madness is an unputdownable journey into the deepest mysteries of our brains.

Renowned, bestselling novelist Chuck Palahniuk takes us behind the scenes of the writing life, with postcards from decades on the road and incredible examination of the power of fiction and the art of storytelling.

In this spellbinding blend of memoir and insight, bestselling author Chuck Palahniuk shares stories and generous advice on what makes writing powerful and what makes for powerful writing.

With advice grounded in years of careful study and a keenly observed life, Palahniuk combines practical advice and concrete examples from beloved classics, his own books, and a "kitchen-table MFA" culled from an evolving circle of beloved authors and artists, with anecdotes, postcards from the road, and much more.

Clear-eyed, sensitive, illuminating, and knowledgeable, Consider This is Palahniuk's love letter to stories and storytellers, booksellers and books themselves. Consider it a classic in the making.

NATIONAL BESTSELLER - A modern classic--both poignant and funny--about a boy with autism who sets out to solve the murder of a neighbor's dog and discovers unexpected truths about himself and the world.

"Disorienting and reorienting the reader to devastating effect.... Suspenseful and harrowing." --The New York Times Book Review

Christopher John Francis Boone knows all the countries of the world and their capitals and every prime number up to 7,057. He relates well to animals but has no understanding of human emotions. He cannot stand to be touched. And he detests the color yellow.

This improbable story of Christopher's quest to investigate the suspicious death of a neighborhood dog makes for one of the most captivating, unusual, and widely heralded novels in recent years.

From internationally bestselling author Benedict Wells, a sweeping novel of love and loss, and of the lives we never get to live

"[D]azzling storytelling...The End of Loneliness is both affecting and accomplished -- and eternal." --John Irving

An exquisitely wrought and utterly absorbing meditation upon life, loss and love. --Ian McEwan

Jules Moreau's childhood is shattered after the sudden death of his parents. Enrolled in boarding school where he and his siblings, Marty and Liz, are forced to live apart, the once vivacious and fearless Jules retreats inward, preferring to live within his memories - until he meets Alva, a kindred soul caught in her own grief. Fifteen years pass and the siblings remain strangers to one another, bound by tragedy and struggling to recover the family they once were. Jules, still adrift, is anchored only by his desires to be a writer and to reunite with Alva, who turned her back on their friendship on the precipice of it becoming more. But, just as it seems they can make amends for time wasted, invisible forces - whether fate or chance - intervene.

A kaleidoscopic family saga told through the fractured lives of the three Moreau siblings, alongside a faltering, recovering love story, The End of Loneliness is a stunning meditation on the power of our memories, of what can be lost and what can never be let go. With inimitable compassion and luminous, affecting prose, Benedict Wells contends with what it means to find a way through life, while never giving up hope you will find someone to go with you.

Chuck Palahniuk showed himself to be his generation's most visionary satirist in this, his first book. Fight Club's estranged narrator leaves his lackluster job when he comes under the thrall of Tyler Durden, an enigmatic young man who holds secret after-hours boxing matches in the basements of bars. There, two men fight "as long as they have to." This is a gloriously original work that exposes the darkness at the core of our modern world.

NEW YORK TIMES BESTSELLER - A TODAY SHOW #ReadWithJenna BOOK CLUB PICK - The unforgettable story of a daredevil female aviator determined to chart her own course in life, at any cost: an "epic trip--through Prohibition and World War II, from Montana to London to present-day Hollywood--and you'll relish every minute" (People).

After being rescued as infants from a sinking ocean liner in 1914, Marian and Jamie Graves are raised by their dissolute uncle in Missoula, Montana. There--after encountering a pair of barnstorming pilots passing through town in beat-up biplanes--Marian commences her lifelong love affair with flight. At fourteen she drops out of school and finds an unexpected and dangerous patron in a wealthy bootlegger who provides a plane and subsidizes her lessons, an arrangement that will haunt her for the rest of her life, even as it allows her to fulfill her destiny: circumnavigating the globe by flying over the North and South Poles.

A century later, Hadley Baxter is cast to play Marian in a film that centers on Marian's disappearance in Antarctica. Vibrant, canny, disgusted with the claustrophobia of Hollywood, Hadley is eager to redefine herself after a romantic film franchise has imprisoned her in the grip of cult celebrity. Her immersion into the character of Marian unfolds, thrillingly, alongside Marian's own story, as the two women's fates--and their hunger for self-determination in vastly different geographies and times--collide. Epic and emotional, meticulously researched and gloriously told, Great Circle is a monumental work of art, and a tremendous leap forward for the prodigiously gifted Maggie Shipstead.

The journey through Middle-earth begins here with J.R.R. Tolkien's classic prelude to his Lord of the Rings trilogy.

"A glorious account of a magnificent adventure, filled with suspense and seasoned with a quiet humor that is irresistible... All those, young or old, who love a fine adventurous tale, beautifully told, will take The Hobbit to their hearts."--The New York Times Book Review

"In a hole in the ground there lived a hobbit." So begins one of the most beloved and delightful tales in the English language--Tolkien's prelude to The Lord of the Rings. Set in the imaginary world of Middle-earth, at once a classic myth and a modern fairy tale, The Hobbit is one of literature's most enduring and well-loved novels.

Bilbo Baggins is a hobbit who enjoys a comfortable, unambitious life, rarely traveling any farther than his pantry or cellar. But his contentment is disturbed when the wizard Gandalf and a company of dwarves arrive on his doorstep one day to whisk him away on an adventure. They have launched a plot to raid the treasure hoard guarded by Smaug the Magnificent, a large and very dangerous dragon. Bilbo reluctantly joins their quest, unaware that on his journey to the Lonely Mountain he will encounter both a magic ring and a frightening creature known as Gollum.

A gargantuan, mind-altering comedy about the Pursuit of Happiness in America

Set in an addicts' halfway house and a tennis academy, and featuring the most endearingly screwed-up family to come along in recent fiction, Infinite Jest explores essential questions about what entertainment is and why it has come to so dominate our lives; about how our desire for entertainment affects our need to connect with other people; and about what the pleasures we choose say about who we are.

Equal parts philosophical quest and screwball comedy, Infinite Jest bends every rule of fiction without sacrificing for a moment its own entertainment value. It is an exuberant, uniquely American exploration of the passions that make us human -- and one of those rare books that renew the idea of what a novel can do.

With a foreword by Tom Bisell.

"The next step in fiction...Edgy, accurate, and darkly witty...Think Beckett, think Pynchon, think Gaddis. Think." --Sven Birkerts, The Atlantic

The acclaimed Pelican Shakespeare series, now in a dazzling new series design

Winner of the 2016 AIGA + Design Observer 50 Books 50 Covers competition

Gold Medal Winner of the 3x3 Illustration Annual No. 14

This edition of A Midsummer Night's Dream is edited with an introduction by Russ McDonald and was recently repackaged with cover art by Manuja Waldia. Waldia received a Gold Medal from the Society of Illustrators for the Pelican Shakespeare series.

The legendary Pelican Shakespeare series features authoritative and meticulously researched texts paired with scholarship by renowned Shakespeareans. Each book includes an essay on the theatrical world of Shakespeare's time, an introduction to the individual play, and a detailed note on the text used. Updated by general editors Stephen Orgel and A. R. Braunmuller, these easy-to-read editions incorporate over thirty years of Shakespeare scholarship undertaken since the original series, edited by Alfred Harbage, appeared between 1956 and 1967. With stunning new covers, definitive texts, and illuminating essays, the Pelican Shakespeare will remain a valued resource for students, teachers, and theater professionals for many years to come.

For more than seventy years, Penguin has been the leading publisher of classic literature in the English-speaking world. With more than 1,700 titles, Penguin Classics represents a global bookshelf of the best works throughout history and across genres and disciplines. Readers trust the series to provide authoritative texts enhanced by introductions and notes by distinguished scholars and contemporary authors, as well as up-to-date translations by award-winning translators.

From #1 New York Times bestselling author Leigh Bardugo comes a mesmerizing tale of power, privilege, and dark magic set among the Ivy League elite.

Galaxy "Alex" Stern is the most unlikely member of Yale's freshman class. Raised in the Los Angeles hinterlands by a hippie mom, Alex dropped out of school early and into a world of shady drug-dealer boyfriends, dead-end jobs, and much, much worse. In fact, by age twenty, she is the sole survivor of a horrific, unsolved multiple homicide. Some might say she's thrown her life away. But at her hospital bed, Alex is offered a second chance: to attend one of the world's most prestigious universities on a full ride. What's the catch, and why her?

Still searching for answers, Alex arrives in New Haven tasked by her mysterious benefactors with monitoring the activities of Yale's secret societies. Their eight windowless "tombs" are the well-known haunts of the rich and powerful, from high-ranking politicos to Wall Street's biggest players. But their occult activities are more sinister and more extraordinary than any paranoid imagination might conceive. They tamper with forbidden magic. They raise the dead. And, sometimes, they prey on the living.

Ninth House is the long-awaited adult debut by the beloved author of Shadow and Bone and Six of Crows. Leigh Bardugo will take her place alongside Lev Grossman and Deborah Harkness as one of the finest practitioners of literary fantasy writing today.

An instant New York Times Bestseller!

Longlisted for the 2019 National Book Award for Fiction, the Carnegie Medal in Fiction, the 2019 Aspen Words Literacy Prize, and the PEN/Hemingway Debut Novel Award

Shortlisted for the 2019 Center for Fiction First Novel Prize

Winner of the 2019 New England Book Award for Fiction!

Named one of the most anticipated books of 2019 by Vulture, Entertainment Weekly, Buzzfeed, Los Angeles Times, Boston Globe, Oprah.com, Huffington Post, The A.V. Club, Nylon, The Week, The Rumpus, The Millions, The Guardian, Publishers Weekly, and more.

"A lyrical work of self-discovery that's shockingly intimate and insistently universal...Not so much briefly gorgeous as permanently stunning." --Ron Charles, The Washington Post

Poet Ocean Vuong's debut novel is a shattering portrait of a family, a first love, and the redemptive power of storytelling

On Earth We're Briefly Gorgeous is a letter from a son to a mother who cannot read. Written when the speaker, Little Dog, is in his late twenties, the letter unearths a family's history that began before he was born -- a history whose epicenter is rooted in Vietnam -- and serves as a doorway into parts of his life his mother has never known, all of it leading to an unforgettable revelation. At once a witness to the fraught yet undeniable love between a single mother and her son, it is also a brutally honest exploration of race, class, and masculinity. Asking questions central to our American moment, immersed as we are in addiction, violence, and trauma, but undergirded by compassion and tenderness, On Earth We're Briefly Gorgeous is as much about the power of telling one's own story as it is about the obliterating silence of not being heard.

With stunning urgency and grace, Ocean Vuong writes of people caught between disparate worlds, and asks how we heal and rescue one another without forsaking who we are. The question of how to survive, and how to make of it a kind of joy, powers the most important debut novel of many years.

Named a Best Book of the Year by:
GQ, Kirkus Reviews, Booklist, Library Journal, TIME, Esquire, The Washington Post, Apple, Good Housekeeping, The New Yorker, The New York Public Library, Elle.com, The Guardian, The A.V. Club, NPR, Lithub, Entertainment Weekly, Vogue.com, The San Francisco Chronicle, Mother Jones, Vanity Fair, The Wall Street Journal Magazine and more!

"I have no doubt this will end up being the best fantasy debut of the year [...] I have absolutely no doubt that [Kuang's] name will be up there with the likes of Robin Hobb and N.K. Jemisin." -- Booknest

A Library Journal, Paste Magazine, Vulture, BookBub, and ENTROPY Best Books pick!

Washington Post 5 Best Science Fiction and Fantasy Novel pick!

A Bustle 30 Best Fiction Books pick!

A brilliantly imaginative talent makes her exciting debut with this epic historical military fantasy, inspired by the bloody history of China's twentieth century and filled with treachery and magic, in the tradition of Ken Liu's Grace of Kings and N.K. Jemisin's Inheritance Trilogy.

When Rin aced the Keju--the Empire-wide test to find the most talented youth to learn at the Academies--it was a shock to everyone: to the test officials, who couldn't believe a war orphan from Rooster Province could pass without cheating; to Rin's guardians, who believed they'd finally be able to marry her off and further their criminal enterprise; and to Rin herself, who realized she was finally free of the servitude and despair that had made up her daily existence. That she got into Sinegard--the most elite military school in Nikan--was even more surprising.

But surprises aren't always good.

Because being a dark-skinned peasant girl from the south is not an easy thing at Sinegard. Targeted from the outset by rival classmates for her color, poverty, and gender, Rin discovers she possesses a lethal, unearthly power--an aptitude for the nearly-mythical art of shamanism. Exploring the depths of her gift with the help of a seemingly insane teacher and psychoactive substances, Rin learns that gods long thought dead are very much alive--and that mastering control over those powers could mean more than just surviving school.

For while the Nikara Empire is at peace, the Federation of Mugen still lurks across a narrow sea. The militarily advanced Federation occupied Nikan for decades after the First Poppy War, and only barely lost the continent in the Second. And while most of the people are complacent to go about their lives, a few are aware that a Third Poppy War is just a spark away . . .

Rin's shamanic powers may be the only way to save her people. But as she finds out more about the god that has chosen her, the vengeful Phoenix, she fears that winning the war may cost her humanity . . . and that it may already be too late.

Growing up on the Upper West Side of New York City in the 1970s, in an apartment filled with dazzling literary and artistic characters, Priscilla Gilman worshiped her brilliant, adoring, and mercurial father, the writer, theater critic, and Yale School of Drama professor Richard Gilman. But when Priscilla was ten years old, her mother, renowned literary agent Lynn Nesbit, abruptly announced that she was ending the marriage. The resulting cascade of disturbing revelations--about her parents' hollow marriage, her father's double life and tortured sexual identity--fundamentally changed Priscilla's perception of her father, as she attempted to protect him from the depression that had long shadowed him.

A wrenching story about what it means to be the daughter of a demanding parent, a revelatory window into the impact of divorce, and a searching reflection on the nature of art and criticism, The Critic's Daughter is an unflinching account of loss and grief--and a radiant testament of forgiveness and love.

Wells's genre-defining novel of time travel

When a Victorian scientist propels himself into the year a.d. 802,701, he is initially delighted to find that suffering has been replaced by beauty, contentment, and peace. Entranced at first by the Eloi, an elfin species descended from man, he soon realizes that these beautiful people are simply remnants of a once-great culture--now weak and childishly afraid of the dark. They have every reason to be afraid: in deep tunnels beneath their paradise lurks another race descended from humanity--the sinister Morlocks. And when the scientist's time machine vanishes, it becomes clear he must search these tunnels if he is ever to return to his own era.

This edition includes a newly established text, a full biographical essay on Wells, a list of further reading, and detailed notes. Marina Warner's introduction considers Wells's development of the "scientific romance" and places the novel in the context of its time.

For more than seventy years, Penguin has been the leading publisher of classic literature in the English-speaking world. With more than 1,700 titles, Penguin Classics represents a global bookshelf of the best works throughout history and across genres and disciplines. Readers trust the series to provide authoritative texts enhanced by introductions and notes by distinguished scholars and contemporary authors, as well as up-to-date translations by award-winning translators.

"A brave and original debut, Weyward is a spellbinding story about what may transpire when the natural world collides with a legacy of witchcraft." --Sarah Penner, New York Times bestselling author of The Lost Apothecary

I am a Weyward, and wild inside.

2019: Under cover of darkness, Kate flees London for ramshackle Weyward Cottage, inherited from a great aunt she barely remembers. With its tumbling ivy and overgrown garden, the cottage is worlds away from the abusive partner who tormented Kate. But she begins to suspect that her great aunt had a secret. One that lurks in the bones of the cottage, hidden ever since the witch-hunts of the 17th century.

1619: Altha is awaiting trial for the murder of a local farmer who was stampeded to death by his herd. As a girl, Altha's mother taught her their magic, a kind not rooted in spell casting but in a deep knowledge of the natural world. But unusual women have always been deemed dangerous, and as the evidence for witchcraft is set out against Altha, she knows it will take all of her powers to maintain her freedom.

1942: As World War II rages, Violet is trapped in her family's grand, crumbling estate. Straitjacketed by societal convention, she longs for the robust education her brother receives--and for her mother, long deceased, who was rumored to have gone mad before her death. The only traces Violet has of her are a locket bearing the initial W and the word weyward scratched into the baseboard of her bedroom.

Weaving together the stories of three extraordinary women across five centuries, Emilia Hart's Weyward is an enthralling novel of female resilience and the transformative power of the natural world.

#1 NEW YORK TIMES BESTSELLER - "Prepare to be entranced by this addictively readable oral history of the great war between humans and zombies."--Entertainment Weekly

We survived the zombie apocalypse, but how many of us are still haunted by that terrible time? We have (temporarily?) defeated the living dead, but at what cost? Told in the haunting and riveting voices of the men and women who witnessed the horror firsthand, World War Z is the only record of the pandemic.

The Zombie War came unthinkably close to eradicating humanity. Max Brooks, driven by the urgency of preserving the acid-etched first-hand experiences of the survivors, traveled across the United States of America and throughout the world, from decimated cities that once teemed with upwards of thirty million souls to the most remote and inhospitable areas of the planet. He recorded the testimony of men, women, and sometimes children who came face-to-face with the living, or at least the undead, hell of that dreadful time. World War Z is the result. Never before have we had access to a document that so powerfully conveys the depth of fear and horror, and also the ineradicable spirit of resistance, that gripped human society through the plague years.

THE INSPIRATION FOR THE MAJOR MOTION PICTURE

"Will spook you for real."--The New York Times Book Review

"Possesses more creativity and zip than entire crates of other new fiction titles. Think Mad Max meets The Hot Zone. . . . It's Apocalypse Now, pandemic-style. Creepy but fascinating."--USA Today

"Will grab you as tightly as a dead man's fist. A."--Entertainment Weekly, EW Pick

"Probably the most topical and literate scare since Orson Welles's War of the Worlds radio broadcast . . . This is action-packed social-political satire with a global view."--Dallas Morning News